Opportunity Information: Apply for HT9425 23 RCRP CA

The DOD Rare Cancers Research Program (RCRP) Concept Award (Funding Opportunity Number HT9425 23 RCRP CA) is a FY23 funding opportunity from the Department of Defense, administered through the Department of the Army USAMRAA, aimed at pushing rare cancer research in bold new directions. It is designed specifically for ideas that are highly innovative, untested, and potentially groundbreaking, with an emphasis on concepts that could open up entirely new avenues of investigation rather than extend or refine projects that are already well underway. In other words, the program is looking for research that takes a real scientific risk because the payoff could be transformative for understanding, preventing, diagnosing, or treating rare cancers.

A key feature of this Concept Award is that preliminary data are not required, which signals that reviewers are expected to weigh the strength and originality of the idea and its potential impact more heavily than existing proof-of-concept results. The intent is to give Principal Investigators room to pursue novel hypotheses and even serendipitous observations, including unexpected findings that might not fit neatly into an established research plan but could lead to major breakthroughs. Because of this, the award is positioned for high-risk, high-reward work where the outcome is uncertain, but the concept is compelling enough that it could meaningfully shift the field if successful.

Applications are expected to clearly explain what is new about the proposed concept and how it will enhance the current knowledge base around rare cancers or establish an innovative course of investigation. The expectation is that a successful project will produce insights, methods, or early findings that can serve as a launchpad for future, larger-scale studies. In practical terms, the Concept Award can function as a catalyst: it funds exploratory work that may generate the initial evidence needed to compete for subsequent research funding and to build a more developed program around a novel idea.

From an administrative standpoint, this is a discretionary opportunity in the Science and Technology and other Research and Development category (CFDA 12.420). The funding instrument types listed include both cooperative agreements and grants. Eligibility is described as unrestricted, meaning it is open to any type of applicant entity, subject to any additional eligibility details that may be provided in the official notice text. The opportunity was created on April 19, 2023, with an original closing date of August 25, 2023. The posting anticipates approximately 20 awards. The listed award ceiling is shown as 0, which typically indicates that a specific maximum was not provided in the summarized fields and would need to be confirmed in the full program announcement or related guidance.

Overall, the DOD RCRP Concept Award is best understood as an early-stage innovation mechanism for rare cancer research: it prioritizes originality and potential impact, supports unconventional or emerging scientific directions, does not require preliminary data, and aims to help investigators generate the foundational results that could justify and enable larger follow-on studies.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DOD, Rare Cancers, Concept Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Apr 19, 2023.
  • Applicants must submit their applications by Aug 25, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 20 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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